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Advanced topics in forensic DNA typing : interpretation / John M. Butler

By: Material type: TextTextAmsterdam : Elsevier Academic Press, [Date of publication not identified]Description: 585 pages : illustrationsContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 9780124052130
Subject(s): LOC classification:
  • RA1057.55 BUT
Contents:
Front Cover; Contributors; ADVANCED TOPICS IN FORENSIC DNA TYPING: INTERPRETATION; Copyright; Dedication; Contents; Foreword; Introduction; NEW MATERIAL IN THIS VOLUME; OVERVIEW OF BOOK CHAPTERS; References; Acknowledgments; Reference; About the Author; Reference; SECTION I -DATA INTERPRETATION; Chapter 1 -- Data Interpretation Overview; PURPOSE OF THIS BOOK; THE INTERPRETATION PROCESS; CHARACTERISTICS OF IDEAL DATA; GUIDANCE FOR DNA INTERPRETATION; A MATCH OR NOT A MATCH: THAT IS THE QUESTION ... ; STR LOCI, KITS, AND POPULATION DATA; SUMMARY; Reading List and Internet Resources. Chapter 2 -- Data, Models, ThresholdsDATA COLLECTION IN ABI GENETIC ANALYZERS11CERTAIN COMMERCIAL EQUIPMENT, INSTRUMENTS, AND MATERIALS ARE IDENTIFIED IN ORDER ... ; MODELS; THRESHOLDS USED IN STR TYPING; SETTING AND USING ANALYTICAL THRESHOLDS; Reading List and Internet Resources; Chapter 3 -- STR Alleles and Amplification Artifacts; INTRODUCTION; OVERVIEW OF THE STR TYPING PROCESS; STR ALLELES AND THEIR MEASUREMENT; VARIANT AND "OFF-LADDER" ALLELES; ARTIFACTS OF STR ALLELE AMPLIFICATION; NON-TEMPLATE ADDITION; STUTTER PRODUCTS; NULL (SILENT) ALLELES; Reading List and Internet Resources. Chapter 4 -- STR Genotypes: Heterozygote Balance, Stochastic Thresholds, Allele, and Concordance StudiesIMPORTANCE OF GENOTYPES VS. ALLELES; PEAK HEIGHT RATIOS; STOCHASTIC THRESHOLDS AND ALLELE DROP-OUT; CONCORDANCE STUDIES AND NULL ALLELES; Reading List and Internet Resources; Chapter 5 -- STR Profiles: Multiplex PCR, Tri-Alleles, Amelogenin, and Partial Profiles; INTRODUCTION; MULTIPLEX PCR CHALLENGES; STR PROFILE EVALUATION; TRI-ALLELIC PATTERNS; GENDER IDENTIFICATION WITH AMELOGENIN; PARTIAL DNA PROFILES; Reading List and Internet Resources; Chapter 6 -- DNA Mixtures; GENERAL INFORMATION. TOOLS FOR MIXTURE INTERPRETATIONELEMENTS OF MIXTURE INTERPRETATION; RESOURCES AND GUIDANCE ON MIXTURE INTERPRETATION; COMPLICATING FACTORS IN MIXTURE DECONVOLUTION; Reading List and Internet Resources; Tools for Mixture Interpretation; Elements of Mixture Interpretation; Resources to Aid Mixture Interpretation; Chapter 7 -- Low-Level DNA and Complex Mixtures; INTERPRETATION CHALLENGES WITH LOW TEMPLATE DNA; LOW-QUANTITY AND LOW-QUALITY DNA; PROBABILISTIC GENOTYPING; HIGH-DENSITY SNP ARRAYS?; MORE POOR-QUALITY SAMPLES BEING SUBMITTED; A COMPLEXITY THRESHOLD?; Reading List and Internet Resources. Chapter 8 -- Troubleshooting Data CollectionINTRODUCTION; PRINCIPLES AND PROCESSES INVOLVED WITH CAPILLARY ELECTROPHORESIS; INSTRUMENT MAINTENANCE & COMMON PROBLEMS; RECOMMENDED STEPS FOR TROUBLESHOOTING; SUMMARY; Reading List and Internet Resources; SECTION II -- STATISTICALINTERPRETATION; Chapter 9 -- Statistical Interpretation Overview; ROLE OF STATISTICS IN FORENSIC DNA; PROBABILITY; STATISTICS; Reading List and Internet Resources; Chapter 10 -- STR Population Data Analysis; INTRODUCTORY GENETIC PRINCIPLES; POPULATION DATA; GENETIC MODELS AND FORMULAS; PRACTICAL CONSIDERATIONS; SUMMARY.
Summary: The first edition of Forensic DNA Typing, published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, Advanced Topics in Forensic DNA Typing: Interpretation. This book builds upon the previous two editions of Forensic DNA Typing books, but with a focus on mixture interpretation and statistical analysis and is a companion to the bestselling Advanced Topics in Forensic DNA Typing: Methodology, published in September 2011. Provides forensic DNA ana
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Holdings
Item type Current library Home library Shelving location Call number Copy number Status Date due Barcode
Books Books Harare Institute of Technology Main Library Harare Institute of Technology Main Library General Collection RA1057.55 BUT (Browse shelf(Opens below)) 1 Available BK002217

Includes index

Includes bibliography

Front Cover; Contributors; ADVANCED TOPICS IN FORENSIC DNA TYPING: INTERPRETATION; Copyright; Dedication; Contents; Foreword; Introduction; NEW MATERIAL IN THIS VOLUME; OVERVIEW OF BOOK CHAPTERS; References; Acknowledgments; Reference; About the Author; Reference; SECTION I -DATA INTERPRETATION; Chapter 1 --
Data Interpretation Overview; PURPOSE OF THIS BOOK; THE INTERPRETATION PROCESS; CHARACTERISTICS OF IDEAL DATA; GUIDANCE FOR DNA INTERPRETATION; A MATCH OR NOT A MATCH: THAT IS THE QUESTION ... ; STR LOCI, KITS, AND POPULATION DATA; SUMMARY; Reading List and Internet Resources. Chapter 2 --
Data, Models, ThresholdsDATA COLLECTION IN ABI GENETIC ANALYZERS11CERTAIN COMMERCIAL EQUIPMENT, INSTRUMENTS, AND MATERIALS ARE IDENTIFIED IN ORDER ... ; MODELS; THRESHOLDS USED IN STR TYPING; SETTING AND USING ANALYTICAL THRESHOLDS; Reading List and Internet Resources; Chapter 3 --
STR Alleles and Amplification Artifacts; INTRODUCTION; OVERVIEW OF THE STR TYPING PROCESS; STR ALLELES AND THEIR MEASUREMENT; VARIANT AND "OFF-LADDER" ALLELES; ARTIFACTS OF STR ALLELE AMPLIFICATION; NON-TEMPLATE ADDITION; STUTTER PRODUCTS; NULL (SILENT) ALLELES; Reading List and Internet Resources. Chapter 4 --
STR Genotypes: Heterozygote Balance, Stochastic Thresholds, Allele, and Concordance StudiesIMPORTANCE OF GENOTYPES VS. ALLELES; PEAK HEIGHT RATIOS; STOCHASTIC THRESHOLDS AND ALLELE DROP-OUT; CONCORDANCE STUDIES AND NULL ALLELES; Reading List and Internet Resources; Chapter 5 --
STR Profiles: Multiplex PCR, Tri-Alleles, Amelogenin, and Partial Profiles; INTRODUCTION; MULTIPLEX PCR CHALLENGES; STR PROFILE EVALUATION; TRI-ALLELIC PATTERNS; GENDER IDENTIFICATION WITH AMELOGENIN; PARTIAL DNA PROFILES; Reading List and Internet Resources; Chapter 6 --
DNA Mixtures; GENERAL INFORMATION. TOOLS FOR MIXTURE INTERPRETATIONELEMENTS OF MIXTURE INTERPRETATION; RESOURCES AND GUIDANCE ON MIXTURE INTERPRETATION; COMPLICATING FACTORS IN MIXTURE DECONVOLUTION; Reading List and Internet Resources; Tools for Mixture Interpretation; Elements of Mixture Interpretation; Resources to Aid Mixture Interpretation; Chapter 7 --
Low-Level DNA and Complex Mixtures; INTERPRETATION CHALLENGES WITH LOW TEMPLATE DNA; LOW-QUANTITY AND LOW-QUALITY DNA; PROBABILISTIC GENOTYPING; HIGH-DENSITY SNP ARRAYS?; MORE POOR-QUALITY SAMPLES BEING SUBMITTED; A COMPLEXITY THRESHOLD?; Reading List and Internet Resources. Chapter 8 --
Troubleshooting Data CollectionINTRODUCTION; PRINCIPLES AND PROCESSES INVOLVED WITH CAPILLARY ELECTROPHORESIS; INSTRUMENT MAINTENANCE & COMMON PROBLEMS; RECOMMENDED STEPS FOR TROUBLESHOOTING; SUMMARY; Reading List and Internet Resources; SECTION II --
STATISTICALINTERPRETATION; Chapter 9 --
Statistical Interpretation Overview; ROLE OF STATISTICS IN FORENSIC DNA; PROBABILITY; STATISTICS; Reading List and Internet Resources; Chapter 10 --
STR Population Data Analysis; INTRODUCTORY GENETIC PRINCIPLES; POPULATION DATA; GENETIC MODELS AND FORMULAS; PRACTICAL CONSIDERATIONS; SUMMARY.


The first edition of Forensic DNA Typing, published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, Advanced Topics in Forensic DNA Typing: Interpretation. This book builds upon the previous two editions of Forensic DNA Typing books, but with a focus on mixture interpretation and statistical analysis and is a companion to the bestselling Advanced Topics in Forensic DNA Typing: Methodology, published in September 2011. Provides forensic DNA ana

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