Advanced topics in forensic DNA typing : interpretation /
Butler, John M. 1969-
Advanced topics in forensic DNA typing : interpretation / John M. Butler - 585 pages : illustrations
Includes index
Includes bibliography
Front Cover; Contributors; ADVANCED TOPICS IN FORENSIC DNA TYPING: INTERPRETATION; Copyright; Dedication; Contents; Foreword; Introduction; NEW MATERIAL IN THIS VOLUME; OVERVIEW OF BOOK CHAPTERS; References; Acknowledgments; Reference; About the Author; Reference; SECTION I -DATA INTERPRETATION; Chapter 1 --
Data Interpretation Overview; PURPOSE OF THIS BOOK; THE INTERPRETATION PROCESS; CHARACTERISTICS OF IDEAL DATA; GUIDANCE FOR DNA INTERPRETATION; A MATCH OR NOT A MATCH: THAT IS THE QUESTION ... ; STR LOCI, KITS, AND POPULATION DATA; SUMMARY; Reading List and Internet Resources. Chapter 2 --
Data, Models, ThresholdsDATA COLLECTION IN ABI GENETIC ANALYZERS11CERTAIN COMMERCIAL EQUIPMENT, INSTRUMENTS, AND MATERIALS ARE IDENTIFIED IN ORDER ... ; MODELS; THRESHOLDS USED IN STR TYPING; SETTING AND USING ANALYTICAL THRESHOLDS; Reading List and Internet Resources; Chapter 3 --
STR Alleles and Amplification Artifacts; INTRODUCTION; OVERVIEW OF THE STR TYPING PROCESS; STR ALLELES AND THEIR MEASUREMENT; VARIANT AND "OFF-LADDER" ALLELES; ARTIFACTS OF STR ALLELE AMPLIFICATION; NON-TEMPLATE ADDITION; STUTTER PRODUCTS; NULL (SILENT) ALLELES; Reading List and Internet Resources. Chapter 4 --
STR Genotypes: Heterozygote Balance, Stochastic Thresholds, Allele, and Concordance StudiesIMPORTANCE OF GENOTYPES VS. ALLELES; PEAK HEIGHT RATIOS; STOCHASTIC THRESHOLDS AND ALLELE DROP-OUT; CONCORDANCE STUDIES AND NULL ALLELES; Reading List and Internet Resources; Chapter 5 --
STR Profiles: Multiplex PCR, Tri-Alleles, Amelogenin, and Partial Profiles; INTRODUCTION; MULTIPLEX PCR CHALLENGES; STR PROFILE EVALUATION; TRI-ALLELIC PATTERNS; GENDER IDENTIFICATION WITH AMELOGENIN; PARTIAL DNA PROFILES; Reading List and Internet Resources; Chapter 6 --
DNA Mixtures; GENERAL INFORMATION. TOOLS FOR MIXTURE INTERPRETATIONELEMENTS OF MIXTURE INTERPRETATION; RESOURCES AND GUIDANCE ON MIXTURE INTERPRETATION; COMPLICATING FACTORS IN MIXTURE DECONVOLUTION; Reading List and Internet Resources; Tools for Mixture Interpretation; Elements of Mixture Interpretation; Resources to Aid Mixture Interpretation; Chapter 7 --
Low-Level DNA and Complex Mixtures; INTERPRETATION CHALLENGES WITH LOW TEMPLATE DNA; LOW-QUANTITY AND LOW-QUALITY DNA; PROBABILISTIC GENOTYPING; HIGH-DENSITY SNP ARRAYS?; MORE POOR-QUALITY SAMPLES BEING SUBMITTED; A COMPLEXITY THRESHOLD?; Reading List and Internet Resources. Chapter 8 --
Troubleshooting Data CollectionINTRODUCTION; PRINCIPLES AND PROCESSES INVOLVED WITH CAPILLARY ELECTROPHORESIS; INSTRUMENT MAINTENANCE & COMMON PROBLEMS; RECOMMENDED STEPS FOR TROUBLESHOOTING; SUMMARY; Reading List and Internet Resources; SECTION II --
STATISTICALINTERPRETATION; Chapter 9 --
Statistical Interpretation Overview; ROLE OF STATISTICS IN FORENSIC DNA; PROBABILITY; STATISTICS; Reading List and Internet Resources; Chapter 10 --
STR Population Data Analysis; INTRODUCTORY GENETIC PRINCIPLES; POPULATION DATA; GENETIC MODELS AND FORMULAS; PRACTICAL CONSIDERATIONS; SUMMARY.
The first edition of Forensic DNA Typing, published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, Advanced Topics in Forensic DNA Typing: Interpretation. This book builds upon the previous two editions of Forensic DNA Typing books, but with a focus on mixture interpretation and statistical analysis and is a companion to the bestselling Advanced Topics in Forensic DNA Typing: Methodology, published in September 2011. Provides forensic DNA ana
9780124052130
DNA fingerprinting --Moral and ethical aspects.
DNA fingerprinting --Congresses.
DNA Fingerprinting --methods
RA1057.55 / BUT
Advanced topics in forensic DNA typing : interpretation / John M. Butler - 585 pages : illustrations
Includes index
Includes bibliography
Front Cover; Contributors; ADVANCED TOPICS IN FORENSIC DNA TYPING: INTERPRETATION; Copyright; Dedication; Contents; Foreword; Introduction; NEW MATERIAL IN THIS VOLUME; OVERVIEW OF BOOK CHAPTERS; References; Acknowledgments; Reference; About the Author; Reference; SECTION I -DATA INTERPRETATION; Chapter 1 --
Data Interpretation Overview; PURPOSE OF THIS BOOK; THE INTERPRETATION PROCESS; CHARACTERISTICS OF IDEAL DATA; GUIDANCE FOR DNA INTERPRETATION; A MATCH OR NOT A MATCH: THAT IS THE QUESTION ... ; STR LOCI, KITS, AND POPULATION DATA; SUMMARY; Reading List and Internet Resources. Chapter 2 --
Data, Models, ThresholdsDATA COLLECTION IN ABI GENETIC ANALYZERS11CERTAIN COMMERCIAL EQUIPMENT, INSTRUMENTS, AND MATERIALS ARE IDENTIFIED IN ORDER ... ; MODELS; THRESHOLDS USED IN STR TYPING; SETTING AND USING ANALYTICAL THRESHOLDS; Reading List and Internet Resources; Chapter 3 --
STR Alleles and Amplification Artifacts; INTRODUCTION; OVERVIEW OF THE STR TYPING PROCESS; STR ALLELES AND THEIR MEASUREMENT; VARIANT AND "OFF-LADDER" ALLELES; ARTIFACTS OF STR ALLELE AMPLIFICATION; NON-TEMPLATE ADDITION; STUTTER PRODUCTS; NULL (SILENT) ALLELES; Reading List and Internet Resources. Chapter 4 --
STR Genotypes: Heterozygote Balance, Stochastic Thresholds, Allele, and Concordance StudiesIMPORTANCE OF GENOTYPES VS. ALLELES; PEAK HEIGHT RATIOS; STOCHASTIC THRESHOLDS AND ALLELE DROP-OUT; CONCORDANCE STUDIES AND NULL ALLELES; Reading List and Internet Resources; Chapter 5 --
STR Profiles: Multiplex PCR, Tri-Alleles, Amelogenin, and Partial Profiles; INTRODUCTION; MULTIPLEX PCR CHALLENGES; STR PROFILE EVALUATION; TRI-ALLELIC PATTERNS; GENDER IDENTIFICATION WITH AMELOGENIN; PARTIAL DNA PROFILES; Reading List and Internet Resources; Chapter 6 --
DNA Mixtures; GENERAL INFORMATION. TOOLS FOR MIXTURE INTERPRETATIONELEMENTS OF MIXTURE INTERPRETATION; RESOURCES AND GUIDANCE ON MIXTURE INTERPRETATION; COMPLICATING FACTORS IN MIXTURE DECONVOLUTION; Reading List and Internet Resources; Tools for Mixture Interpretation; Elements of Mixture Interpretation; Resources to Aid Mixture Interpretation; Chapter 7 --
Low-Level DNA and Complex Mixtures; INTERPRETATION CHALLENGES WITH LOW TEMPLATE DNA; LOW-QUANTITY AND LOW-QUALITY DNA; PROBABILISTIC GENOTYPING; HIGH-DENSITY SNP ARRAYS?; MORE POOR-QUALITY SAMPLES BEING SUBMITTED; A COMPLEXITY THRESHOLD?; Reading List and Internet Resources. Chapter 8 --
Troubleshooting Data CollectionINTRODUCTION; PRINCIPLES AND PROCESSES INVOLVED WITH CAPILLARY ELECTROPHORESIS; INSTRUMENT MAINTENANCE & COMMON PROBLEMS; RECOMMENDED STEPS FOR TROUBLESHOOTING; SUMMARY; Reading List and Internet Resources; SECTION II --
STATISTICALINTERPRETATION; Chapter 9 --
Statistical Interpretation Overview; ROLE OF STATISTICS IN FORENSIC DNA; PROBABILITY; STATISTICS; Reading List and Internet Resources; Chapter 10 --
STR Population Data Analysis; INTRODUCTORY GENETIC PRINCIPLES; POPULATION DATA; GENETIC MODELS AND FORMULAS; PRACTICAL CONSIDERATIONS; SUMMARY.
The first edition of Forensic DNA Typing, published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, Advanced Topics in Forensic DNA Typing: Interpretation. This book builds upon the previous two editions of Forensic DNA Typing books, but with a focus on mixture interpretation and statistical analysis and is a companion to the bestselling Advanced Topics in Forensic DNA Typing: Methodology, published in September 2011. Provides forensic DNA ana
9780124052130
DNA fingerprinting --Moral and ethical aspects.
DNA fingerprinting --Congresses.
DNA Fingerprinting --methods
RA1057.55 / BUT