Carbohydrates in drug discovery and development : synthesis and application - Tiwari, Vinod Kumar (San Diego : Elsevier, 2020)
1. Recent trends and challenges on carbohydrate-based molecular scaffolding: general consideration toward impact of carbohydrates in drug discovery and development2. Heparin mimetics as tools for modulation of biology and therapy3. Bioactive C-glycosides inspired from natural products toward therapeutics4. 3-Deoxy-d-manno-oct-2-ulosonic acid (Kdo) derivatives in antibacterial drug discovery5. Sialic acid-containing molecules in drug discovery and development6. Glycan microarray: Toward drug discovery and development7. Recent developments in the synthesis of biologically relevant Iinositol derivatives8. Iminosugars in medicinal chemistry9. Carbohydrate-protein interactions: Enhancing multivalency effects through statistical rebinding10. Carbo-click in drug discovery and development: Opportunity and challenges11. Glycohybrids molecule in medicinal chemistry: Present status and future prospective12. Biologically active carbohydrate-containing macrocycles13. Carbohydrate-based antibiotics: Opportunities and challenges14. Carbohydrate-based anti-bacterial and anti-cancer vaccines15. Opportunity of plant oligosaccharides and polysaccharides in drug development16. N-acetylgalactosamine (GalNAc)-conjugates: Delivering oligonucleotide drugs to the liver
Includes index
Keywords: Carbohydrates -- Therapeutic use; Pharmaceutical chemistry