TY - BOOK AU - Shen Chang-Hui TI - Diagnostic molecular biology SN - 9780128028230 AV - RB43.7 SHE PY - 2019/// CY - London PB - Academic Press KW - Molecular diagnosis KW - Molecular Biology -- methods KW - MEDICAL -- Evidence-Based Medicine N1 - Includes index; Includes Bibliography; Part I 1. Nucleic Acids: DNA and RNA 2. Nucleic Acid-Based Cellular Activities 3. Gene Expression: Transcription of the Genetic Code 4. Gene Expression: Translation of the Genetic Code 5. The Genome Part II 6. Extraction and Purification of Nucleic Acids and Proteins 7. Detection and Analysis of Nucleic Acids 8. Quantification and Analysis of Proteins 9. Amplification of Nucleic Acids 10. Characterization of Nucleic Acids and Proteins 11. Techniques in Sequencing 12. Genome and Transcriptome Analysis Part III 13. Molecular Diagnosis of Chromosomal Disorders 14. Molecular Diagnosis of Mutation and Inherited Diseases 15. Molecular Diagnosis of Infectious Diseases 16. Guidance for Molecular Clinical Laboratory N2 - Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear, concise manner to aid in the comprehension of this complex subject. Each technique described in this book is explained within its conceptual framework to enhance understanding. The targeted approach covers the principles of molecular biology including the basic knowledge of nucleic acids, proteins, and genomes as well as the basic techniques and instrumentations that are often used in the field of molecular biology with detailed procedures and explanations. This book also covers the applications of the principles and techniques currently employed in the clinical laboratory ER -